A peptide derived from endostatin ameliorates organ fibrosis.
Sci Transl Med. 2012 May 30; 4(136):136ra71
John Varga
03 Jul 2012
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New Finding, Technical Advance
This paper makes a significant contribution toward the development of fibrosis therapies by a) generating a modified natural peptide with potent anti-fibrotic activity, and b) validating its biological efficacy using an innovative combination of in vitro, ex vivo and in vivo assessments. Fibrosing disorders are responsible for up...
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