Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis.
Science. 2012 Jun 8; 336(6086):1314-7
Neil Andrew Robert Gow and Amy Whittington
01 Oct 2012
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Interesting Hypothesis, New Finding
In this systematically thorough study, Iliev et al. emphasize two key points -- the mammalian gut microbiome is not the territory of bacteria alone, and the innate immune receptor dectin-1 is partially responsible for recognition of fungi in the gut. Specifically, the role of murine Clec7 is investigated in its capacity to curtail...
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