Mass spectral molecular networking of living microbial colonies.
Proc Natl Acad Sci U S A. 2012 May 14
Watrous J, Roach P, Alexandrov T, Heath BS, ..., Moore BS, Laskin J, Bandeira N, Dorrestein PC. Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC. Proc Natl Acad Sci U S A. 2012 May 14
In the kind of advance that happens only a few times per decade, this paper describes how the small molecules in and around a living bacterial colony can be identified and quantified over time and space. The method rapidly generated profiles of complex inter-organism signal responses at the adjacent edges of pairs of different o such...
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