Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome.
Cell. 2012 May 16
Stephen Dalton and Amar Singh
20 Jul 2012
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New Finding, Technical Advance
DNA methylation and hydroxymethylation of cytosine residues have an important role in stem cell biology, differentiation and early embryonic development. Current methodologies, however, have been unable to distinguish between these epigenetic marks on a genome-wide level. This current study by Yu et al., describes a novel technique...
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