IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma.
Clin Cancer Res. 2012; 18(9):2490-501
Gorovets D, Kannan K, Shen R, Kastenhuber ER ... Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT Clin Cancer Res. 2012; 18(9):2490-501
This paper suggests a new classification based on molecular profile of lower grade diffuse astrocytic glioma predictive of overall survival.
World Health Organization (WHO) II and III diffuse astrocytic gliomas are defined by histopathology; however, lately it became clear that they represent a spectrum of closely related pathologies....
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