J Exp Med. 2012 May 7; 209(5):925-33
Autotaxin is an extracellular phosphodiesterase that cleaves many lipid and non-lipid substrates. It has been suggested as a drug target for metastatic cancer, fibrotic disease, obesity, and neuropathic pain. In this article, the authors present new data that suggest that autotaxin is involved also in the pathogenesis of arthritis....
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