The major alpha-tubulin K40 acetyltransferase alphaTAT1 promotes rapid ciliogenesis and efficient mechanosensation.
Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21517-22
Yanmin Yang and Carl Victor Lundin
06 Jun 2011
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Confirmation, New Finding
This is an excellent study that presents definitive work on the long sought-after alpha-tubulin acetyltransferase (alphaTAT).
The work was concurrent with another study published in Nature {1}, and both studies point to a conserved role for MEC17 in catalyzing the acetylation of alpha-tubulin K40. Shida et al. provide significant...
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