Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels.
Sci Signal. 2010; 3(145):ra77
Alexei Tepikin
22 Nov 2010
The study demonstrates an interesting and important connection between TRPC (transient receptor potential canonical) channels, Ca2+ responses, actin remodelling and cell migration.
The authors utilized electrophysiology, Ca2+ imaging, advanced molecular biology and cell migration assays to probe the role of TRPC channels in cell...
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