Single-cell analysis reveals that insulation maintains signaling specificity between two yeast MAPK pathways with common components.
Sci Signal. 2010; 3(144):ra75
Patterson JC, Klimenko ES, Thorner J. Sci Signal. 2010; 3(144):ra75
This paper is interesting because it provides insight into mechanisms whereby mitogen-activated protein kinase (MAPK) cascades that share multiple upstream components are activated with specificity by different stimuli.
The authors studied the mating factor-stimulated Fus3 MAPK and osmotic stress-stimulated Hog1 MAPK pathways in...
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