Molecular mechanism of calcium channel regulation in the fight-or-flight response.
Sci Signal. 2010; 3(141):ra70
Fuller MD, Emrick MA, Sadilek M, Scheuer T, Catterall WA. Sci Signal. 2010; 3(141):ra70
This manuscript is the last in a series of studies from the Catterall laboratory on the mechanism by which protein kinase enhances an L-type calcium channel activity. This regulation is a key mechanism by which heart rate is enhanced during the fight or flight response and the underlying molecular details had puzzled researchers for...
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