Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse.
Sci Signal. 2010; 3(121):ra36
Purbhoo MA, Liu H, Oddos S, Owen DM ... Pageon SV, French PM, Rudd CE, Davis DM Purbhoo MA, Liu H, Oddos S, Owen DM, Neil MA, Pageon SV, French PM, Rudd CE, Davis DM Sci Signal. 2010; 3(121):ra36
In this technically elegant paper, the authors report the very interesting finding of interplay between vesicular pools of the transmembrane adaptor protein linker for activation of T cells (LAT) and early T cell receptor (TCR)-signaling microclusters. These studies open the door to further exploration of the relationship between...
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