Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling.
Sci Signal. 2010; 3(115):ra24
Alexei Tepikin
19 Jul 2010
|
New Finding
This elegant study describes redox regulation of Ca2+ signalling and investigates the physiological consequences of this regulation for functioning of T cells.
The main finding reported in this paper is the ability of hydrogen peroxide to oxidise and inhibit Ca2+ influx mediated by store-operated ORAI1 Ca2+ channels. Advanced biophysical...
INDIVIDUAL SUBSCRIPTIONS
Get instant access to Article Recommendations from more than 5,000 expert scientists and clinical researchers, assisted by 5,000 associates, by taking out a monthly subscription. The first month of your subscription will be free of charge.
Start your personal subscription today.
Subscribe for $9.95/monthINSTITUTIONAL SUBSCRIPTIONS
Send a recommendation to your institution's librarian or information manager to request an extended free trial for all users.
Recommend to your LibrarianIf you are a librarian or information manager, you may request an extended free trial for your academic or corporate institution.
Request an Institutional Trialyour institution might be eligible for free access via our sponsorship scheme. Check our sponsorship page.
If you think you should be able to access this content, please contact us.