A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution.
Science. 2010 Jul 23; 329(5990):436-9
Hu Q, Milenkovic L, Jin H, Scott MP, Nachury MV, Spiliotis ET, Nelson WJ. Science. 2010 Jul 23; 329(5990):436-9
I was excited reading this article because it is an important step towards understanding the function of septins in higher organisms.
Septins have originally been identified as cell division (cdc) mutants in yeast, where they are localized at the septum (hence the name) in the bud neck between the mother and daughter cell {1}....
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