Mitochondria supply membranes for autophagosome biogenesis during starvation.
Cell. 2010 May 14; 141(4):656-67
Hailey DW, Rambold AS, Satpute-Krishnan P, Mitra K, Sougrat R, Kim PK, Lippincott-Schwartz J Cell. 2010 May 14; 141(4):656-67
These authors propose that the outer membrane of the mitochondria is the main source of the autophagosomal lipid bilayers. Using fluorescent microscopy analyses in cells they showed that two sets of marker proteins were found to co-localize in the membranes of both mitochondria and autophagosomes. The results need to be considered...
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