Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor.
Sci Signal. 2010; 3(107):ra8
Peter J Fuller
05 May 2010
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New Finding
This paper is exceptional. Just when you thought that you might understand steroid receptor signalling, the basis of resistance and the modulation of the response to glucocorticoids, a further nuance is added to the complexity.
The group of Kino et al. have identified a non-coding RNA, Gas5, which represses the glucocorticoid receptor....
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