Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.
Cell. 2012 Feb 3; 148(3):434-46
Sebastien Gagneux
14 Jun 2012
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New Finding
This paper presents an excellent example of how human genetic diversity can influence the effectiveness of treatment against an infectious disease (i.e. tuberculosis). The authors start by presenting convincing functional data generated in Mycobacterium marinum and the zebrafish model, which they then complement with human genetic...
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