A 5-hydroxymethyl furfural reducing enzyme encoded by the Saccharomyces cerevisiae ADH6 gene conveys HMF tolerance.
Yeast. 2006 Apr 30; 23(6):455-64
In addition to using all sugars, microbial strains for use in biofuel production must be resistant to the compounds produced or released during biomass degradation. This study overexpressed the gene ADH6 in yeast, which enabled it to metabolize the toxic by-product hydroxymethyl-furfural.
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