Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.
Nucleic Acids Res. 2012 Mar 1; 40(5):2345-56
Meier JL, Montgomery DC, Dervan PB. Nucleic Acids Res. 2012 Mar 1; 40(5):2345-56
This paper propels the field of artificial control of transcription by showing that aromatic (aryl) groups appended to the turn domain of small hairpin polyamide compounds unexpectedly confers improved nuclear uptake in cultured mammalian cells. This kind of improvement offers an approach to better target delivery of this interesting...
Get instant access to Article Recommendations from more than 5,000 expert scientists and clinical researchers, assisted by 5,000 associates, by taking out a monthly subscription. The first month of your subscription will be free of charge.
Start your personal subscription today.Subscribe for $9.95/month
Send a recommendation to your institution's librarian or information manager to request an extended free trial for all users.Recommend to your Librarian
If you are a librarian or information manager, you may request an extended free trial for your academic or corporate institution.Request an Institutional Trial
your institution might be eligible for free access via our sponsorship scheme. Check our sponsorship page.
If you think you should be able to access this content, please contact us.