Structure of the mitotic checkpoint complex.
Nature. 2012; 484(7393):208-13
Chao WC, Kulkarni K, Zhang Z, Kong EH, Barford D. Nature. 2012; 484(7393):208-13
In this paper, the structure of the mitotic checkpoint complex (MCC) of fission yeast was solved, revealing key molecular insights into how the assembly of mitotic arrest deficient 2 (Mad2), mitotic arrest deficient 2 (Mad3) and cell division cycle protein 20 (Cdc20) is regulated and how this complex is able to inhibit anaphase-promoting...
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