Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Nucleic Acids Res. 2012 Jan 28
Schaefer MH, Wanker EE, Andrade-Navarro MA. Nucleic Acids Res. 2012 Jan 28
Expansion of sequences of repeated CAGs in genes, leading to repeated glutamines in the resulting protein, is associated with several neurodegenerative diseases. The current study investigates the normal role of these sequences using analysis at the gene and protein level in an attempt to shed light on the role their expansion plays...
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