A rapid assay for affinity and kinetics of molecular interactions with nucleic acids.
Nucleic Acids Res. 2011 Dec 30
This is an interesting new technique that allows for rapid acquisition of affinity or kinetic measurements of small molecules and proteins that interact with nucleic acids. The assay is based upon the nitrocellulose filter-binding assay, a popular method for measuring the affinity of protein-nucleic interactions.
To measure affinity...
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