Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking.
J Am Chem Soc. 2012 Jan 11; 134(1):75-8
Almeida AM, Li R, Gellman SH. J Am Chem Soc. 2012 Jan 11; 134(1):75-8
This manuscript examines the potential of disulphide crosslinks between cysteine groups to stabilize and propagate parallel beta-sheets. The study supports earlier observations regarding the infrequency of disulphide bonds between Cys residues in adjacent strands of parallel beta-sheets within proteins, but suggests that such bridges...
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