Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.
Neuron. 2011 Dec 8; 72(5):721-33
Witten IB, Steinberg EE, Lee SY, Davidson TJ, ..., Stuber GD, Tye KM, Janak PH, Deisseroth K. Witten IB, Steinberg EE, Lee SY, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C, Stuber GD, Tye KM, Janak PH, Deisseroth K. Neuron. 2011 Dec 8; 72(5):721-33
The authors introduce two novel transgenic Cre recombinase-driver rat lines to a technical arena dominated by mouse models. They describe Long Evans rat lines specifically expressing Cre recombinase under the control of either a choline acetyltransferase (Chat) or tyrosine hydroxylase (TH) promoter. The specificity and functionality...
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