Paradoxical reversal learning enhancement by stress or prefrontal cortical damage: rescue with BDNF.
Nat Neurosci. 2011 Dec; 14(12):1507-9
Graybeal C, Feyder M, Schulman E, Saksida LM, Bussey TJ, Brigman JL, Holmes A Nat Neurosci. 2011 Dec; 14(12):1507-9
This paper shows that stress, which is commonly thought of as a negative response, actually improves reversal learning. Reversal learning is a measure of cognitive function that can be disrupted by chronic drug exposure. This is unfortunate for drug-dependent individuals who are striving for abstinence, as reversal learning involves...
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