Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF.
Sci Signal. 2011 Sep 13; 4(190):ra58
Rony Seger1 and Zhong Yao2
05 Oct 2011
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New Finding
c-Raf is a central node in the integration of extracellular signals to MEK/extracellular signal-regulated kinase (ERK) and their downstream cellular processes. As such, its activity is tightly regulated by a complex mechanism that includes a set of activating processes and negative feedback loops. Here, the authors show another, mode...
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