Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.
Cell. 2011 Sep 2; 146(5):772-84
Dang EV, Barbi J, Yang HY, Jinasena D, ..., Semenza GL, Dang CV, Pardoll DM, Pan F. Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim Y, Yen HR, Luo W, Zeller K, Shimoda L, Topalian SL, Semenza GL, Dang CV, Pardoll DM, Pan F. Cell. 2011 Sep 2; 146(5):772-84
In agreement with previous evaluations, we recognize the proposed model in this paper as interesting and potentially important for targeting immune-mediated pathologies.
The authors convincingly showed that the metabolic sensor, hypoxia-inducible factor (HIF)-1alpha, has multifunctional roles in controlling the balance of pathogenic...
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