Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.
Cell. 2011 Sep 2; 146(5):772-84
Rachel R Caspi and Reiko Horai
30 Apr 2012
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New Finding, Novel Drug Target
In agreement with previous evaluations, we recognize the proposed model in this paper as interesting and potentially important for targeting immune-mediated pathologies.
The authors convincingly showed that the metabolic sensor, hypoxia-inducible factor (HIF)-1alpha, has multifunctional roles in controlling the balance of pathogenic...
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