Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei.
Neural Dev. 2011; 6:29
Kamal Sharma
13 Jul 2011
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New Finding
It is tricky to define a neuron’s identity. Is it unique to be a dopamine neuron in the midst of many that are not? It depends. Blaess et al. provide evidence that the dopamine neuron subtypes emerge early in embryonic development and Lammel et al. {1} show the functional significance of these dopamine neuron subtypes.
Dopamine neurons <10Hz), but innervate distinct targets located in the striatum and lateral shell of nucleus accumbens, respectively. Dopamine neurons of the medial posterior VTA fire with high frequency (>...
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