PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells.
Sci Signal. 2009; 2(77):ra32
Kathleen J Green1 and Bhushan Desai2
17 Nov 2009
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Interesting Hypothesis, New Finding
While the importance of so-called “cross-talk” between cell-cell and cell-matrix adhesion complexes is frequently stressed as playing a key role in tumor progression, relatively few concrete examples have been detailed at a molecular level of resolution. This paper is important as it reveals the formation of a novel complex between...
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