The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling.
Sci Signal. 2009; 2(76):ra29
Ed Laufer
27 Oct 2009
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New Finding
This and two related papers, one by Liem et al. {1} and another by Endoh-Yamagami et al. {2}, demonstrate that Kif7, a kinesin-related motor protein, is involved in the mammalian hedgehog pathway. This is noteworthy because it had been unclear whether this homolog of Drosophila Costal2 had this activity.
Previous morphant studies...
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