Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.
Sci Signal. 2009; 2(87):ra51
Alexey Belkin
12 Nov 2009
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New Finding, Technical Advance
This interesting paper by Humphries et al. reported a novel proteomics-based approach for the analysis of integrin-associated signaling complexes.
Integrin-ligand interactions orchestrate a vast range of cellular functions through membrane-associated signaling complexes and mechanosensitive linkage to the cytoskeleton. Yet, anyspecific...
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