Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.
Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2635-40
Joel Moss
19 Feb 2009
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Interesting Hypothesis, New Finding
Lymphangioleiomyomatosis (LAM), a rare cystic lung disease found primarily in women, results from the proliferation of the "LAM cell", which has mutations in the tuberous sclerosis complex (TSC) genes. It is unclear why LAM is found primarily in women. In this article, Yu et al. demonstrate that pulmonary metastasis and survival of...
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