Time-lapse analysis and mathematical characterization elucidate novel mechanisms underlying muscle morphogenesis.
PLoS Genet. 2008; 4(10):e1000219
Snow CJ, Goody M, Kelly MW, Oster EC, Jones R, Khalil A, Henry CA. PLoS Genet. 2008; 4(10):e1000219
I like this paper because it is a tour de force of quantitative analysis of cell behaviors in vivo. It represents perfectly the direction in which morphogenesis studies need to go. The authors combine rigorous application of traditional methods for quantifying cell behavior and also introduce a very promising new mathematical approach...
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