Sickle cell vasoocclusion and rescue in a microfluidic device.
Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51):20496-500
The findings presented in this article provide an important new framework to understand sickle vasoocclusion as well as study potential pharmacological inhibitors of this process.
The authors validate a novel microfluidic in vitro approach to study the dynamic events underlying vasoocclusion and resolution of vasoocclusion in sickle...
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