GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
Science. 2007 Nov 23; 318(5854):1266-73
Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, ..., Yao XJ, Weis WI, Stevens RC, Kobilka BK. Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK. Science. 2007 Nov 23; 318(5854):1266-73
Some important integral membrane protein structures have recently been determined in Protein Structure Initiative funded projects. In this example X-ray crystallography was used to determine the structure of a beta2-adrenergic receptor.
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