Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC.
J Cell Sci. 2007 Sep 15; 120(Pt 18):3200-6
Andreas Wodarz
17 Sep 2007
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Confirmation
This paper clarifies the role of the small GTPase cdc42 during the asymmetric division of neural stem cells in Drosophila.
A previous study by Hutterer et al. {1} found that overexpression of dominant negative or constitutively active cdc42 had no major effect on the asymmetric division of Drosophila neuroblasts.
This study now...
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