A genomic code for nucleosome positioning.
Nature. 2006 Aug 17; 442(7104):772-8
Segal E, Fondufe-Mittendorf Y, Chen L, Thåström A, Field Y, Moore IK, Wang JP, Widom J. Nature. 2006 Aug 17; 442(7104):772-8
This article is important because it identifies sequence preference for the positioning of nucleosomes on the genome.
By using computational and experimental methods conjointly, the authors identify stretches of DNA which are enriched in nucleosomes.
These results suggest a mechanism to unmask transcription factor binding sites...
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