Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes.
Med Immunol. 2006; 5:1
Kendall Smith
30 May 2006
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Controversial, Interesting Hypothesis, New Finding, Technical Advance
This contribution suggests that a paradigm shift is called for in the construction of vaccines for HIV, one that focuses on the immune responses of HIV-negative individuals, instead of those already infected.
Using bioinformatics to identify potential T cell epitopes predicted to be from conserved regions of the HIV genome that should...
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