Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa.
Proc Natl Acad Sci U S A. 2005 Nov 1; 102(44):15942-7
Ramachandran S, Deshpande O, Roseman CC, Rosenberg NA, Feldman MW, Cavalli-Sforza LL Proc Natl Acad Sci U S A. 2005 Nov 1; 102(44):15942-7
This paper reports a striking linear relationship between genetic and geographic distance, using ~800 microsatellites typed in a globally distributed sample of humans.
Diversity levels are best explained by an African origin, in accordance with the findings of Prugnolle et al. (Curr Biol 2005, 15:R159-60 [PMID:15753023]).
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