Millisecond-timescale, genetically targeted optical control of neural activity.
Nat Neurosci. 2005 Sep; 8(9):1263-8
Matteo Carandini
31 Jul 2006
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Technical Advance
This exciting new technique uses lentiviral gene delivery to make neurons of the cerebral cortex express an algal photopigment, therefore making them respond to light.
Once this technique is applied to preparations in vivo, and paired to optical imaging methods to detect activity, it will allow one to study connectivity with unprecedented...
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