ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat.
J Cell Biol. 2002 Oct 14; 159(1):69-78
Michael Roth
27 Nov 2002
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New Finding
This paper shows that ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) is an effector of the small GTP binding protein ARF in addition to stimulating GTP hydrolysis on ARF to terminate its activity.
Rather than promoting the uncoating of COPI vesicles that form in response to activated ARF, ARFGAP1 promotes vesicle formation...
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