Paradigm for industrial strain improvement identifies sodium acetate tolerance loci in Zymomonas mobilis and Saccharomyces cerevisiae.
Proc Natl Acad Sci U S A. 2010 Jun 8; 107(23):10395-400
Yang S, Land ML, Klingeman DM, Pelletier DA, ..., Martin SL, Guo HB, Smith JC, Brown SD. Yang S, Land ML, Klingeman DM, Pelletier DA, Lu TY, Martin SL, Guo HB, Smith JC, Brown SD. Proc Natl Acad Sci U S A. 2010 Jun 8; 107(23):10395-400
This paper is one of the first to illustrate the application of microbial genomic resequencing and microarray studies to determine the genome changes responsible for improved bioprocessing traits in strains obtained after random chemical mutagenesis and selection.
The bacterium Zymomonas mobilis has promise for industrial-strain...
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