Bioinformatics | Theory & Simulation | Structural Genomics
SymD server: A platform for detecting internally symmetric protein structures
Chin-Hsien (Emily) Tai, Rohit Paul, Dukka KC, Jeffery Shilling, Byungkook Lee*
*Corresponding author: Byungkook Lee
Molecular Modeling and Bioinformatics Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
F1000Posters 2011, 2: 1324 (poster) [ENGLISH]
Poster [1.26 MB]
19th Annual International Conference on Intelligent Systems for Molecular Biology and 10th European Conference on Computational Biology 2011 (ISMB/ECCB), 17 - 19 Jul 2011, V7
Many protein domains are made of repeating units of similar structures arranged in a beautifully symmetric manner. The mechanism of such an arrangement, the biological function and the evolutionary history of symmetric proteins are largely unknown.
To answer these questions, we first developed a program, called Symmetry Detection (SymD), to detect internally symmetric protein structures.
Here, we report on the development of the SymD web server, a dynamic platform based on Galaxy to determine if a protein is symmetric and to visualize the structure interactively.
No relevant conflicts of interest declared.
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