Endocrine & Metabolic Pharmacology | Renal Immunology & Pathology (incl. Glomerular Diseases) | Methods for Diagnostic & Therapeutic Studies
Number of repeated steroid pulse therapies with tonsillectomy influences the period between initial therapy and clinical remission in patients with IgA nephropathy
Hiroyuki Komatsu*, Shouichi Fujimoto, Masao Kikuchi, Yuji Sato, Kazuo Kitamura
*Corresponding author: Hiroyuki Komatsu
The First Department of Internal Medicine, University of Miyazaki Hospital, Miyazaki, Japan
F1000Posters 2011, 2: 1158 (slide presentation) [ENGLISH]
Slide Presentation [274.5 KB]
Presented at
48th Congress of the European Renal Association and European Dialysis and Transplant Association 2011,
23 - 26 Jun 2011, F-255
This prospective, non-randomized controlled study verifies whether repeated courses of steroid pulse therapy with tonsillectomy improves the clinical remission rate of IgA nephropathy.
Thirty-five patients underwent one course of steroid (methylprednisolone 0.5 × 3 consecutive days) pulse therapy with tonsillectomy, and 33 received two courses of the same therapy followed by oral prednisolone (initial dosage 0.5 mg/kg/day) for 12 to 18 months.
Increasing the number of courses of steroid pulse therapy with tonsillectomy can shorten the period between initial therapy and clinical remission in patients with IgA nephropathy.
No relevant conflicts of interest declared.
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