Immunopharmacology & Hematologic Pharmacology | Methods for Diagnostic & Therapeutic Studies | Multiple Sclerosis & Related Disorders
Cause of death in patients with multiple sclerosis: The 21-year long-term follow-up study
George C Ebers*, Douglas S Goodin, Anthony T Reder, Gary Cutter, Marcelo Kremenchutzky, Joel Oger, Dawn Langdon, Mark Rametta, Karola Beckmann, Volker Knappertz
*Corresponding author: George C Ebers
University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
F1000Posters 2011, 2: 866 (poster) [ENGLISH]
Poster [373.45 KB]
21st Meeting of the European Neurological Society 2011, 28 - 31 May 2011, P429
This study examined the underlying causes-of-death in 81 deceased patients identified 21 years after their participation in the randomised controlled trial of interferon beta-1b (IFNB-1b; Betaferon®) in multiple sclerosis.
In this cohort of patients, a significant survival advantage in favor of early IFNB-1b treatment versus placebo was found. A total of 82% of deaths with cause-of-death information were adjudicated to be MS-related.
No relevant conflicts of interest declared.
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