Cardiovascular Pharmacology | General Pharmacology
Atropine increases the positive adrenergic effects of norepinephrine: a pilot study
AF Kalmar*, Marloes Weening, Michel MRF Struys, Thomas WL Scheeren
*Corresponding author: AF Kalmar
Anaesthesiology, University Medical Center Groningen (UMCG), Groningen, Netherlands
F1000Posters 2013, 4: 84 (poster) [English]
Poster [0 KB]
Euroanaesthesia 2012, 9 - 12 Jun 2012, P000
University Medical Center Groningen (UMCG)
Atropine is a competitive antagonist of cholinergic receptors and is widely used to blunt the increased vagal tone that is often caused by surgical manipulations. In clinical anaesthesia practice it is almost exclusively used to treat bradycardia.
The haemodynamic effect of atropine is more distinct in the presence of norepinephrine (NOR). This study reveals that in patients receiving low-dose NOR, an advantageous haemodynamic effect can be achieved with the administration of 0.5mg atropine.
No relevant competing interests disclosed.
Please note that most posters on this site present work that is preliminary in nature and has not been peer reviewed.
This poster is open access subject to the CC BY Creative Commons 3.0 License