Cardiovascular Pharmacology | Heart Failure | Acute Cardiovascular Problems
Galectin-3, cardiovascular risk factors, and outcome in the general population
Rudolf A de Boer*, Dirk J Van Veldhuisen, Ron T Gansevoort, Anneke C Muller Kobold, Herman HW Silljé, Wiek H Van Gilst, Hans L Hillege, Stephan JL Bakker, Pim Van Der Harst
*Corresponding author: Rudolf A de Boer
Departments of Cardiology, Internal Medicine, Laboratory Medicine, and Epidemiology, University Medical Center Groningen (UMCG), Groningen, Netherlands
F1000Posters 2013, 4: 25 (poster) [English]
Poster [392.43 KB]
European Society of Cardiology Congress 2010, 28 Aug - 1 Sep 2010, P000
University Medical Center Groningen (UMCG)
Galectin-3, a biomarker of fibrosis and inflammation, predicts outcome in subjects with heart failure. The association of galectin-3 with cardiovascular (CV) risk factors and mortality in the general population remains to be established.
Galectin-3 levels are associated with CV risk factors and this effect is modified by gender. Higher galectin-3 levels are associated with increased mortality rates in the general population. This underscores the potential involvement of galectin-3 in CV disease.
No relevant competing interests disclosed.
BG Medicine, Inc (Waltham, MA, USA), 0000
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