Neurobiology of Disease & Regeneration | Headache
Preferential susceptibility and propagation of spreading depression in superficial cortical layers
Volodymyr B Bogdanov*, Tanye Y Tang, Sylvie Multon, Sergey A Mamilov, Anatolij G Misyura, Jean Schoenen, Yuongo S Ju, KC Brennan
*Corresponding author: Volodymyr B Bogdanov
Department of Neurology, University of Utah, Salt Lake City, UT, USA
F1000Posters 2012, 3: 663 (poster) [English]
Poster [1.01 MB]
54th American Headache Society Annual Meeting 2012, 21 - 24 Jun 2012, P70
We expected that cortical spreading depression (CSD) susceptibility might vary by cortical depth.
We conclude that CSD has a susceptibility and tropism for superficial cortical layers, both in vitro and in vivo.
Induction of CSD with minimal necessary conditions for a more naturalistic model of migraine aura.
No relevant competing interests disclosed.
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