Pharmacokinetics & Drug Delivery | Musculoskeletal & Dermatologic Pharmacology | Molecular Pharmacology | Hair Diseases
Stimulation of hair growth in humans by cell-secreted proteins
Gail K Naughton*, Craig Ziering, Neil Sadick, David Perez-Meza, Mark Hubka, Danielle Ehrlich, Michael Zimber, Jonathan Mansbridge
*Corresponding author: Gail K Naughton
Histogen, Inc., San Diego, CA, USA
F1000Posters 2012, 3: 425 (poster) [English]
Poster [1.82 MB] | Recommended by F1000Prime
Presented at
Society of Investigative Dermatology Annual Meeting 2012,
8 - 11 May 2012, 519
To evaluate a bioengineered human cell-derived formulation, termed Hair Stimulating Complex (HSC), on the effects of hair growth activity in males and females with androgenetic alopecia.
In three clinical studies HSC treatment resulted in a statistically significant increase across hair growth parameters. The safety and efficacy results seen with HSC represent a novel regenerative medicine approach in hair growth treatment for both men and women.
The 48 week data from the Phase I/II study will be evaluated at the end of 2012, with plans to submit an IND in 2013 for commencement of a Phase IIb/III study in men and women involving increased dosing with HSC.
Corresponding author Gail Naughton and several of the authors are employees of or own stock in Histogen Inc.
Please note that most posters on this site present work that is preliminary in nature and has not been peer reviewed.
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