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Pharmacokinetics & Drug Delivery Evaluations

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SECTION HEADS

  • Photo of Gordon Amidon

    Gordon Amidon

    College Pharmacy, Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA

  • Photo of Leslie Benet

    Leslie Benet

    Department of Biopharmaceutical Sciences , University of California, San Francisco, CA, USA

  • Photo of Frank Gonzalez

    Frank Gonzalez

    Center for Cancer Research, Laboratory of Metabolism, National Cancer Institute, NIH, Bethesda, Maryland, USA

Section Topics

  • » Drug delivery (including gene therapy & stem cells as delivery systems; blood-brain barrier; liposomes, polymers & drug delivery)
  • » Drug-drug, drug-disease, drug-nondrug remedy interactions
  • » Metabolism (phase I & phase II enzymes)
  • » Pharmacokinetics, pharmacodynamics & bioavailability
  • » Therapeutic drug monitoring
  • » Transporters plus biliary & renal elimination

LATEST EVALUATION

Kajihara and co-workers report the total synthesis and biological evaluation of a homogeneously glycosylated interferon-β (IFN-β). Like other glycoproteins, the in vivo half-life and biological activity of IFN-β is highly dependent on the presence and...

Justin Chalker, The University of Tulsa, USA. F1000 Chemical Biology

6 Recommended

TOP RATED ARTICLE THIS WEEK [FREE TO VIEW]

10
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.

Bollag G, Hirth P, Tsai J, Zhang J, ..., Flaherty KT, Xu X, Nathanson KL, Nolop K. Nature. 2010 Sep 30; 467(7315):596-9

3 Evaluations, most recent by

Miles Congreve, Heptares Therapeutics Ltd, UK. F1000 Pharmacology & Drug Discovery

  • New Finding
  • Confirmation
  • Technical Advance
  • Clinical Trial

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