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Musculoskeletal & Dermatologic Pharmacology Evaluations

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SECTION HEADS

  • Photo of Margaret Buckingham

    Margaret Buckingham

    Departement de Biologie du Developpement, Institut Pasteur, Paris, France

  • Photo of David Glass

    David Glass

    Department of Muscle Diseases, Novartis Institutes for Biomedical Research, Cambridge, MA, USA

Section Topics

  • » Bone pharmacology
  • » DNA repair in human skin
  • » Differentiation in skeletal muscle
  • » Genodermatoses, dermatologic therapeutics, particularly in the area of skin cancer treatment & prevention
  • » Muscle pharmacology (non-dystrophy)
  • » Pharmacogenomics of skeletal muscle
  • » Skeletal muscle diseases
  • » Skin diseases, including gene therapy for skin disease
  • » Ubiquitination in skeletal muscle
  • » Very broad basic science & clinical interests

LATEST EVALUATION

In their paper, Kashani-Sabet and coworkers set out to define how pleckstrin homology domain-interacting protein (PHIP), highly overexpressed in melanoma {1}, contributes to tumorigenesis. Consistent with PHIP's known ability to interact with the...

Steven A Rosenzweig, Medical University of South Carolina, USA. F1000 Physiology

6 Recommended

TOP RATED ARTICLE THIS WEEK [FREE TO VIEW]

6
Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis.

De Semir D, Nosrati M, Bezrookove V, Dar AA, ..., Miller JR, Sagebiel RW, Debs R, Kashani-Sabet M. Proc Natl Acad Sci U S A. 2012 May 1; 109(18):7067-72

1 Evaluation, most recent by

Steven A Rosenzweig, Medical University of South Carolina, USA. F1000 Physiology

  • New Finding
  • Interesting Hypothesis
  • Novel Drug Target

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